Inherited ClumpingAfter CSHL professor Rob Martienssen, who led the research team, about one tenth our DNA stands aloof, spent his time in tightly packed clumps as heterochromatin, and unwinding only to replicate when a cell divides. Plants and animals both of the resulting DNA molecules – to the surprise of many – It was observed withdrawn form clumps in the same places, as did the original.
– The dense packing of heterochromatin hides the DNA sequence of the cellular machinery that reads its genetic information, so the DNA in heterochromatin is ‘silenced. ‘The genes contained therein effectively turned off. Is surprisingly divide the clumping even after cells, says Dr. Martienssen, ‘it has always been a mystery how modifications of histones could be inherited. ‘A few years ago, however, his group and others solved this mystery. They found that histone modification is known as RNA interference, or RNAi controlled by complex cellular mechanisms.. Long DNA molecules almost miraculously cram into the nucleus , which are almost a million times smaller than them.The number of people will be affected by Alzheimer’s and dementia on an epidemic Haste grows, and to devastate the skyrocketing financial and personal cost economies in the world and health systems, and far too many families, said William Thies , chief medical & scientific officer told the Alzheimer’s Association. We have to fight against Alzheimer a priority before it is too late. 80th there is hope, There are lots medications in late-stage clinical trial for Alzheimer which show promise of to slow or stop the the progression of the disease That, combination with progress in the the early detection, has the landscape the landscape.