For the study

For the study, mice were manipulated by gene targeted mutations that increase the signaling activity Platelet Derived Growth Factor Receptor-alpha . Increased PDGFRA activation in embryos leads to connective tissue hyperplasia and disrupts organ function and increased PDGFRA activation in adult mice cause systemic fibrotic disease in multiple organs. Loss of tumor suppressor gene accelerated when combined with fibrosis PDGFRA activation, a possible new role in the regulation of tumor suppressors revealed fibrotic diseases .

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check all about the treatment

The package was a wholly owned subsidiary from Johnson & Johnson called Kite Merger Sub, done A depositary for the offer is advised Johnson & Johnson, such as of expiration of the first offer period, a total of some 17,030 shares of Cougar Biotechnology ordinary shares duly tendered and not withdrawn, was. Roughly 84.4 percent of shares outstanding out of Cougar Biotechnology common stock All the shares which were offered properly and do not properly withdrawn during the initial offering period have has been accepted for payment.