Oral mucositis is a common and occurs often debilitating inflammation and ulcers in the mouth as a complication of cancer treatment. PMX – 30063 is currently in a Phase 2 clinical trial in patients with acute bacterial skin and skin structure infections Staphylococcus Staphylococcus bacteria. ‘to alleviate the ability of PMX – 30063 for the treatment of ulcerative mucositis in pre-clinical studies is significant and exciting,’commented Stephen T. Chief Medical Officer at Biomodels where the studies were performed, and a Professor of Oral Medicine at Harvard School of Dental Medicine and world-renowned expert in the clinical treatment and research of cancer related mucosal toxicities.
With the ability to potentially administer PMX – 30063 topically may also advantages over systemic approaches. .. . We continue to be inspired by the breadth of therapeutic possibilities for our defensin-mimetic compounds, said Nicholas Landekic, President and Chief Executive Officer of PolyMedix. There is a great need for effective treatment options for the hundreds of thousands of patients each year who take advantage ulcerative lesions develop as a result of their cancer treatment. A recent study from Northwestern University quantified the cost of additional resource on the management of patients with mucositis in over $ 17,000 as well as lengthening hospital stays, making this an expensive and serious medical problem.In a phase 1 clinical study INNO-206 was in doses up to six times the standard variation dosing doxorubicin without increasing observed adverse events via those who historical manages saw doxorubicin. U.S. The phase 1 trial of of 35 patients with with various cancers with INNO-206 treated skin were a partial tumor reduction of 20 patients were stable disease over the study. All three of partial remissions appeared with the higher dose range of dosage study of the safety.
On soft tissue sarcomastissue sarcomas are group of relatively infrequently tumors that can in a variety of websites, the soft tissue, includes skin, muscles and internal organs incurred. The limbs , trunk and the retroperitoneum or head and neck to make (10 percent on which these at which these cancer develop into. The three main types of soft tissue sarcoma is leiomyosarcoma, malignant fibrous histiocytoma and liposarcoma. Most tumors occur in the soft tissue including the heart, skin, In general and retroperitoneum.